His funeral. A., King, A. C., Fielding, R. A., Glynn, N. W., Pahor, M. The impact of cognitive behavioral group training on event-free survival in patients with myocardial infarction: The ENRICHD experience. B., Sink, K., Gill, T. M., King, A. C., Miller, M. E., Guralnik, J., Katula, J., Church, T., Manini, T., Reid, K. F., McDermott, M. M. The MAT-sf: Identifying Risk for Major Mobility Disability. Fielding, R. A., Rejeski, W. J., Blair, S., Church, T., Espeland, M. A., Gill, T. M., Guralnik, J. M., Hsu, F., Katula, J., King, A. C., Kritchevsky, S. B., McDermott, M. M., Miller, M. E., Nayfield, S., Newman, A. Robert M. Kaplan has served as Chief Science Officer at the US Agency for Health Care Research and Quality (AHRQ) and Associate Director of the National Institutes of Health, where he led the behavioral and social sciences programs. No significant effect on event-free survival was associated with individual therapy alone. Free delivery worldwide on over 20 million titles. The company is headquartered in Wollongong, New South Wales, Australia. We here illustrate a quantification of the difference between objective and subjective risks.The objective risks (or chances) can be obtained from traditional 22 tables by calculating the positive (+LR) and negative (-LR) likelihood ratios. Rochlin, D. H., Lee, C. M., Scheuter, C. n., Platchek, T. n., Kaplan, R. M., Milstein, A. n. Questioning the Benefit of Statins for Low-risk Populations-Medical Misinformation or Scientific Evidence? Sensitivity analyses indicated that results were relatively robust to varied assumptions.The PA intervention costs and QALYs gained are comparable to those found in other studies. Although the Enhancing Recovery in Coronary Heart Disease (ENRICHD) treatment was designed to include individual therapy and cognitive behavioral group training for patients with depression and/or low perceived social support, only 31% of treated participants received group training. in terms of outcomes that are meaningful to patients. Bott, N. T., Sheckter, C. C., Yang, D., Peters, S., Brady, B., Plowman, S., Borson, S., Leff, B., Kaplan, R. M., Platchek, T., Milstein, A. Definitive data from large long-term randomized trials are lacking.To determine whether a long-term, structured, moderate-intensity physical activity program is associated with a lower risk for frailty and whether frailty status alters the effect of physical activity on the reduction in major mobility disability (MMD) risk.Multicenter, single-blind, randomized trial.8 centers in the United States.1635 community-dwelling adults, aged 70 to 89 years, with functional limitations.A structured, moderate-intensity physical activity program incorporating aerobic, resistance, and flexibility activities or a health education program consisting of workshops and stretching exercises.Frailty, as defined by the SOF (Study of Osteoporotic Fractures) index, at baseline and 6, 12, and 24 months, and MMD, defined as the inability to walk 400 m, for up to 3.5 years.Over 24 months of follow-up, the risk for frailty (n= 1623) was not statistically significantly different in the physical activity versus the health education group (adjusted prevalence difference, -0.021 [95% CI, -0.049 to 0.007]). These include the EQ-5D, the Health Utilities Index (HUI), the self-administered Quality of Well-being Scale (QWB-SA), and the Health and Activities Limitation Index (HALex). In older adults reduced mobility is common and is an independent risk factor for morbidity, hospitalization, disability, and mortality. Biography ID: 12846404 . and 'is it worth it?') Robert Kaplan; Found 609 results for. In total, 194 men who were biopsy negative for prostate cancer were randomly assigned to complete 2 preference assessment modules, either conjoint analysis and a rating scale module or conjoint analysis and a time tradeoff module. He is also director of the UCLA/RAND health services training program and PI of the UCLA/RAND CDC Prevention Research Center. The PA program consisted of center-based exercise sessions 3x weekly for 8 weeks, 2x weekly for weeks 9 to 24 and weekly behavioral counseling for 10 weeks. Robert M. Kaplan in the United States of America. Rating scales were rated as easiest to use and respondents were more satisfied with rating scales and conjoint in comparison to time tradeoffs. doi:10.2105/AJPH.2018.304857). Three articles address (1) standardizing methods for conducting cost-effectiveness and cost-utility analyses, (2) providing examples to illustrate progress in applying these methods to evaluate interventions delivered in whole or in part in clinical settings, and (3) providing nonclinical intervention examples selected to highlight the challenges and opportunities for evaluating the cost-effectiveness of interventions in more diverse settings. Lives in New York, NY. Robert Kaplan brings together extensive data to make the case that health care priorities in the United States are sorely misplaced. Rochlin, D. H., Lee, C., Scheuter, C., Milstein, A., Kaplan, R. M. Systems Delivery Innovation for Alzheimer Disease. King, A. C., Salvo, D., Banda, J. Baseline frailty status did not modify the effect of physical activity on reducing incident MMD (P for interaction= 0.91).Frailty status was neither an entry criterion nor a randomization stratum.A structured, moderate-intensity physical activity program was not associated with a reduced risk for frailty over 2 years among sedentary, community-dwelling older adults. The physical activity and exercise intervention resulted in statistically significantly lower decline in eGFRCysC over 2 years compared with the health education arm (mean difference, 0.96 mL/min/1.73 m2; 95% CI, 0.02-1.91 mL/min/1.73 m2) and lower odds of rapid eGFRCysC decline (odds ratio, 0.79; 95% CI, 0.65-0.97).Conclusions and Relevance: Results of this ancillary analysis of a randomized clinical trial showed that when compared with health education, a physical activity and exercise intervention slowed the rate of decline in eGFRCysC among community-dwelling sedentary older adults. Schmaling, K. B., Landon, H. S., Nguyen, T. B., Kaplan, R. M. Influence of a COVID-19 vaccine's effectiveness and safety profile on vaccination acceptance. 1968-1973 PUBLICATIONS BOOKS . The 22 table with inverted axes starts with the communication of a test result and presumes that the communication of bad news (whether right or false) will induce 'Perceived Anxiety' while good news will induce 'Perceived Safety'. No significant differences were found across dynapenia and obesity status for all other metabolic components (P>.05). Robert D. Kaplan - Career Reflections Author. In adjusted models, measures of mobility and physical inactivity were generally not associated with sleep-wake disturbances, using continuous or categorical variables.In a large sample of sedentary community-dwelling elderly adults with functional limitations, sleep-wake disturbances were prevalent but only mildly severe and were generally not associated with mobility impairment or physical inactivity. However, more research is necessary to conclusively rule out medical care as a mediator between education and health. Groessl, E. J., Kaplan, R. M., Castro Sweet, C. M., Church, T., Espeland, M. A., Gill, T. M., Glynn, N. W., King, A. C., Kritchevsky, S., Manini, T., McDermott, M. M., Reid, K. F., Rushing, J., Pahor, M. Cost-effectiveness of the LIFE Physical Activity Intervention for Older Adults at Increased Risk for Mobility Disability. Noncommunicable diseases are now the primary cause of death worldwide and most are strongly linked to behavior. OBJECTIVE: Incidence rates of ankylosing spondylitis (AS) among males versus females are poorly understood. Additionally, the presence of dynapenia did not increase cardiometabolic disease risk in either obese or nonobese older adults. Groessl, E. J., Kaplan, R. M., Sweet, C. M., Church, T., Espeland, M. A., Gill, T. M., Glynn, N. W., King, A. C., Kritchevsky, S., Manini, T., McDermott, M. M., Reid, K. F., Rushing, J., Pahor, M. GENETIC MODERATORS OF THE IMPACT OF PHYSICAL ACTIVITY ON DEPRESSIVE SYMPTOMS, Dotson, V. M., Hsu, F. C., Langaee, T. Y., McDonough, C. W., King, A. C., Cohen, R. A., Newman, A. Additionally, NDYN-O demonstrated higher diastolic blood pressure compared with DYN-O (70.910.1 vs 67.79.7, P.001). Rare Classic Car Preview. Baseline and long-term follow-up (2.6 years) health-related quality of life data were collected as a secondary outcome. Kaplan, R. M., Gold, M., Duffy, S. Q., Miller, N., Glassman, J. R., Chambers, D. A., Ganiats, T. G., Berndt, S., Wilson, D. K. Standards for economic analyses of interventions for the field of health psychology and behavioral medicine. The interpretation of screening results is also affected by several known biases. Robert M Kaplan The Maudsley Hospital, reopened in January 1923, became the centre of British psychiatric research and achieved a world-wide reputation. Yet U.S. citizens lag behind their global peers in life expectancy and quality of life. Older people who lose mobility are less likely to remain in the community; demonstrate higher rates of morbidity, mortality, and hospitalizations; and experience a poorer quality of life. In a multistate model, the hazard ratios for comparisons of physical activity with health education were 0.87 (CI, 0.73 to 1.03) for the transition from no MMD to MMD; 0.52 (CI, 0.10 to 2.67) for no MMD to death; 1.33 (CI, 0.99 to 1.77) for MMD to no MMD; and 1.92 (CI, 1.15 to 3.20) for MMD to death.The intention-to-treat principle was maintained for MMD burden and first transition out of no MMD, but not for subsequent transitions.A structured physical activity program reduced the MMD burden for an extended period, in part through enhanced recovery after the onset of disability and diminished risk for subsequent disability episodes.National Institute on Aging, National Institutes of Health. This multisite RCT compared physical activity to health education among 1,635 randomly assigned sedentary older adults at risk for mobility disability in 2010-2011. Download Record Provide Feedback. To test whether a long term, structured physical activity program compared with a health education program reduces the risk of serious fall injuries among sedentary older people with functional limitations.Multicenter, single blinded randomized trial (Lifestyle Interventions and Independence for Elders (LIFE) study).Eight centers across the United States, February 2010 to December 2011.1635 sedentary adults aged 70-89 years with functional limitations, defined as a short physical performance battery score 9, but who were able to walk 400 m.A permuted block algorithm stratified by field center and sex was used to allocate interventions. February 1994 Issue. Last updated 4 months ago. The mean of 0.630 is 0.070 lower than a comparison group of healthy older adults. The outcome was respondents' reported likelihood of receiving a vaccine for the coronavirus. In order to make better use of scarce resources, cost-effectiveness methodologies have been developed to evaluate how to produce the most health within the constraints of available resources. The comparison intervention consisted of weekly education meetings for 24 weeks, and then monthly for 6 months. This pilot work examined associations of brain grey matter volumes (GMV) with perceived fatigability in older adults to elucidate disablement mechanisms. Covariates included clinic site, body mass index, age, sex, baseline score, comorbidity, and use of angiotensin receptor blockers or ACE inhibitors. OBJECTIVE: The authors describe a comprehensive care model for Alzheimer disease (AD) that improves value within 1-3 years after implementation by leveraging targeted outpatient chronic care management, cognitively protective acute care, and timely caregiver support.METHODS: Using current best evidence, expert opinion, and macroeconomic modeling, the authors designed a comprehensive care model for AD that improves the quality of care while reducing total per capita healthcare spending by more than 15%. The methods are general and can be used to estimate the cost-effectiveness of social and environmental interventions in addition to traditional medical and surgical treatments. He is also director of the UCLA/RAND health services training program and PI of the UCLA/RAND CDC Prevention Research Center. This button displays the currently selected search type. Intervention attendance was associated with higher health-related quality of life for both groups. 1974 Medical School . Dismiss. A., Bailey, C., Charpentier, P., Hawthorne-Jones, G., Mignosa, B., Lewis, L., Williamson, J., Sink, K. M., Hendrie, H. C., Rapp, S. R., Verghese, J., Woolard, N., Espeland, M., Jennings, J., Wilson, V. K., Pepine, C. J., Ariet, M., Handberg, E., Deluca, D., Hill, J., Szady, A., Chupp, G. L., Flynn, G. M., Gill, T. M., Hankinson, J. L., Vaz Fragoso, C. A., Groessl, E. J., Kaplan, R. M. Effects of Mental Health on the Costs of Care for Chronic Illnesses: In Reply. 2018 o 8:00 UTC na Court 2, Stellenbosch, South Africa. Assuming a diversion rate of 50% based on previous studies, national savings range from $230 million to $1.0 billion annually. Foreign Correspondent. Each team then evaluated the impact of the evidence found in ClinicalTrials.gov on the conclusions in the review.Across the five reviews, the number of studies that had both a registry record and a publication varied widely, from none in one review to 43% of all studies identified in another. The ability of our field to communicate cost-effectiveness data to policy makers, employers, and insurers that incorporates implementation costs is central to the likelihood of our interventions being adopted by practitioners and reimbursed by payers. View details for DOI 10.1001/jamainternmed.2022.1449, View details for Web of Science ID 000788118600200. Fragoso, C. A., Miller, M. E., Fielding, R. A., King, A. C., Kritchevsky, S. B., McDermott, M. M., Myers, V., Newman, A. The relationship between race/ethnicity, other potential risk factors, and the risk of incident diabetes was estimated using Cox proportional hazards models from which hazard ratios (HRs) and 95% CIs were computed.Participants were aged 63 years on average at baseline. Jacobsen, P. B., Prasad, R., Villani, J., Lee, C., Rochlin, D., Scheuter, C., Kaplan, R. M., Freedland, K. E., Manber, R., Kanaan, J., Wilson, D. K. Economic analysis in behavioral health: Toward application of standardized methodologies. A., Brubaker, P. H., Mihalko, S. L., Jennings, J. M., Hadley, E. C., Romashkan, S., Patel, K., Bonds, D., Mcdermott, M. M., Spring, B., Hauser, J., Kerwin, D., Domanchuk, K., Graff, R., Rego, A., Church, T. S., Blair, S. N., Myers, V. H., Monce, R., Britt, N. E., Harris, M., McGucken, A., Rodarte, R., Millet, H. K., Tudor-Locke, C., Butitta, B. P., Donatto, S. G., Cocreham, S. H., King, A. C., Castro, C. M., Haskell, W. L., Stafford, R. S., Pruitt, L. A., Yank, V., Berra, K., Bell, C., Thiessen, R. M., Youngman, K. P., Virgen, S. B., Maldonado, E., Tarin, K. N., Klaftenegger, H., Prosak, C. A., Campero, I., Garcia, D. M., Soto, J., Chio, L., Hoskins, D., Fielding, R. A., Nelson, M. E., Folta, S. C., Phillips, E. M., Liu, C. K., McDavitt, E. C., Reid, K. F., Kim, D. R., Pasha, E. P., Kim, W. S., Krol, J. M., Beard, V. E., Tsiroyannis, E. X., Hau, C., Marsiske, M., Sandesara, B. D., Black, M. L., Burk, W. L., Hoover, B. M., Knaggs, J. D., Marena, W. C., Korytov, I., Curtis, S. D., Lorow, M. S., Goswami, C. S., Lewis, M. A., Kamen, M., Bitz, J. N., Stanton, B. K., Hicks, T. T., Gay, C. W., Xie, C., Morris, H. L., Singletary, F. F., Causer, J., Yonce, S., Radcliff, K. A., Smith, M., Scott, J. S., Rodriguez, M. M., Fitch, M. S., Dunn, M. C., Schllesinger, J. Q., Newman, A. Fitzgerald, J. D., Johnson, L., Hire, D. G., Ambrosius, W. T., Anton, S. D., Dodson, J. Using hospital discharge data for the period 2007-16, we compared acute myocardial infarction (AMI) hospitalization rates in San Diego County and the rest of the state before and after the demonstration project started. Costs for this PA program for older adults are comparable to those of other PA interventions. At baseline, the 2 groups were well balanced by age, comorbidity, and baseline eGFRCysC. The Pittsburgh Fatigability Scale measured physical and mental fatigability (score 0-50; higher physical fatigability15; higher mental fatigability13). Buford, T. W., Hsu, F., Brinkley, T. E., Carter, C. S., Church, T. S., Dodson, J. Sweeney, A., Freedland, K. E., Resnicow, K., Wilson, D. K., Kaplan, R. M. Health-Related Quality of Life Measurement in Public Health. View details for DOI 10.1377/hlthaff.2018.0443, View details for Web of Science ID 000463962900016. South Africa . The mean HVLT-R delayed recall scores were 7.22 for the physical activity group vs 7.25 for the health education group (mean difference, -0.03 words [95% CI, -0.29 to 0.24 words], P=.84). Robert D. Kaplan is a contributing editor at The Atlantic, a senior fellow at the Center for a New American Security in Washington and the author, most recently, of Asia's Cauldron: The South . Physical inactivity was defined according to sedentary time, as a percentage of accelerometry wear time with activity of <100 counts/min; participants in the top quartile of sedentary time were classified as having a high sedentary time. Data for this study were analyzed from March 29, 2021, to February 28, 2022.Interventions: Structured, 2-year, partially supervised, moderate-intensity physical activity and exercise (strength, flexibility) intervention compared with a health education control intervention with 2-year follow-up. Of the 173 total ClinicalTrials.gov records identified across the five projects, between 11 and 43% did not have an associated publication. This polymorphism is known to influence a variety of physiological adaptions to exercise. A subsample (n=29; age=77.25.5; 86% female) of participants from the Lifestyle Interventions and Independence for Elders (LIFE) Study was utilized to quantify GMV for regions of interest in the basal ganglia and limbic system normalized to intracranial volume.

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